EGCG is one of a group of antioxidants called flavonoids found in plants. They have been linked to a variety of health benefits seen in diets rich in fruits and vegetables, such as protecting against cancer or reducing the risk of heart disease.

Antioxidant May Protect Brain

In the study, published in the Journal of Neuroscience, researchers studied the effects of treating mice genetically altered to develop Alzheimer’s disease with high doses of the green tea antioxidant.

After several months of daily injections of EGCG, the results showed that the nerve cells of treated mice generated as much as 54% fewer beta-amyloid protein than nontreated mice nerve cells.

“The findings suggest that a concentrated component of green tea can decrease brain beta-amyloid plaque formation,” says researcher Jun Tan, PhD, MD, director of the Neuroimmunology Laboratory at the University of South Florida, in a news release. “If beta-amyloid pathology in this Alzheimer’s mouse model is representative of Alzheimer’s disease pathology in humans, EGCG dietary supplementation may be effective in preventing and treating the disease.”